Tuesday, August 28, 2012

1.What is Alzheimer's disease? 2. Dr. Mercola Interviews Dr. Perlmutter - Alzheimer's Disease Prevention


Here is a good video explanation of Alzheimer's Disease, illustrated by
simple, powerful, diagrammatic animations.

Sourced from the tv channel of

Alzheimer's Association 

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 The Correlation of Gluten and Alzheimer's Disease

  Alzheimer's Prevention: Dr. Mercola Interviews Dr. Perlmutter

September 29, 2013

DISCUSSION SUMMARY - THE MAIN POINTS:

Three tests are recommended by Dr. David Perlmutter (DP) to predict Alzheimer's; the first is the Cyrex test. This is a test for antibodies related to gluten sensitivity.
 
Two other tests recommended that are potent predictors of Alzheimer’s disease specifically are:
  • "Fasting blood sugar, as this is a powerful predictor of your risk for Alzheimer’s disease. In this interview, he discusses research showing a very direct correlation between your fasting blood sugar and the rate at which your brain shrinks.  The higher your fasting blood sugar, the greater your risk. Interestingly, brain shrinkage occurs at blood sugar levels that are currently considered within the normal range (90-100), and even small elevations of blood sugar directly correlate to increased risk for having shrinkage of your hippocampus, your memory center, which is the hallmark of Alzheimer’s disease."
  • "Hemoglobin A1c. This is a marker of your average blood sugar over about a three-to four-month period of time. Again, there’s a striking correlation between hemoglobin A1c and the rate at which your brain is shrinking."


IS THERE HOPE FOR THOSE FOUND TO BE AT RISK?
  • Rule number one: You can change your genetic destiny (GD)
"We interact with our genome every moment of our lives, and we can do so positively (by keeping our blood sugar low) to allow the genes to express reduced inflammation, which increase the production of life-giving antioxidants."
In other words our GD is NOT fixed - we can CHANGE our genetic destiny by how we live since our physical, emotional, mental, nutritional, etc. states influence our genetic expression. So it makes sense to live in a way that allows our genetic expression its full potential for health (eg. by avoiding a high sugar, high calorie diet, and opting for Mediterranean-type diets or high (good) fats diet instead). Cf. the 6 TIPS below.
Note: Your diet is under your control the way some other factors may not be and so it is within your means to influence your genetic expression in a huge, desirable and achievable way.
  • Rule number two: You can change your GD to grow new brain cells, 
"specifically in the hippocampus... Your brain’s memory center regenerates. You are constantly growing new brain cells into your 50s, 60s, 80s, and 90s – throughout your lifetime – through a process called neurogenesis."
In other words you can grow back your memory center, the hippocampus, the part that is affected by Alzheimers.
According to Dr. Perlmutter: You should be able to grow new brain cells provided you follow 'lifestyle strategies' which 'promote neurogenesis and the regrowth of brain cells'.


THE WAY FORWARD (- Gluten + > Ketogenic Shift):
"These Lifestyle Strategies target a specific gene pathway called BDNF or brain-derived neurotrophic factor, which promotes brain cell growth and connectivity as demonstrated on MRI scans and include:
  1. Aerobic exercise. "In a 1-year study, individuals who exercised GREW and EXPANDED the brain’s memory center by 1-2% per annum which would have continued to decline in size otherwise." "It’s not just that the brain got bigger, but the memory function improved in a time in which there are no medications or whatsoever that have any effect on improving memory."
    Suggested: 20 minutes exercise daily. DP
  2. Reducing overall calorie intake - for ketogenic metabolism (burning fat not carbs for fuel)
  3. Reducing carbohydrate intake (avoiding gluten)
  4. Increasing HEALTHY FAT intake (avoid transfat) eg. eggs, avocado, nuts, oily fish**
  5. Increasing your omega-3 fat intake (DHA) and reduce consumption of damaged omega-6 fats (processed vegetable oils) in order to balance your omega-3 to omega-6 ratio. (He prefers krill oil to fish oil here, as krill oil also contains astaxanthin, which appears to be particularly beneficial for brain health, as it is a carotenoid that is very “focused” on reducing damage caused by free radicals to FAT (and your brain is 60 to 70 percent FAT)." 
  6. To Sum: "reduce calorie consumption, increase fat consumption, take a DHA supplement, get aerobic exercise – and you’re going to turn on your gene pathway to grow new brain cells." His advice means you have the chance to take some preventative / delay-it action before it happens. Afterall, the best time to fix a roof is when the sun is shining. Don't wait till it's pouring!
Dr. David Perlmutter, author of Grain Brain: ** "Whether it’s organic butter, clarified butter called ghee, or lots of pure fat called organic virgin olive oil or coconut oil, nuts and seeds, free-range chicken, or wild salmon, these are high-fat foods. Avocado, one of my favorites."- Sept 29, 2013
Dr. Joseph Mercola: "...the best fuel for the brain, the super fuel for the brain, according to Dr. George Cahill who’s written on ketosis, is ketones. It’s fat that we mobilize when we’ve been able to get rid of the carbohydrate and introduce coconut oil and other sources of (good) fat into the diet."
 Dr. Joseph Mercola: "The prescription you advocated to reduce Alzheimer’s actually is the exact same prescription that’s recommended to reduce the two other major epidemics, both of which are larger than Alzheimer’s; heart disease and the emerging one, cancer."



For the full article go here >


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